New Challenges for Cancer Systems Biomedicine

フォーマット:

電子ブック

責任表示:

edited by Alberto d’Onofrio, Paola Cerrai, Alberto Gandolfi

言語:

英語

出版情報:

Milano : Springer Milan : Imprint: Springer, 2012

形態:

XI, 398 p : digital

著者名:

• d’Onofrio, Alberto
• Cerrai, Paola
• Gandolfi, Alberto
• SpringerLink (Online service)

シリーズ名:

SIMAI Springer Series ;

目次情報:

Part I Towards a Comprehensive Theory of Cancer Growth
Combining Game Theory and Graph Theory to Model Interactions between Cells in the Tumor Microenvironment
Growth as the Root of all Evil in Carcinomas: Synergy between pH Buffering and Anti-Angiogenesis prevents Emergence of Hallmarks of Cancer
Phase Transitions in Cancer
Part II Cancer Related Signalling Pathways
Spatio-Temporal Modelling of Intracellular Signalling Pathways: Transcription Factors, Negative Feedback Systems and Oscillations
Understanding Cell Fate Decisions by Identifying Crucial System Dynamics
Modelling Biochemical Pathways with the Calculus of Looping Sequences
Dynamic Simulations of Pathways Downstream of TGFβ, Wnt and EGF-Family Growth Factors, in Colorectal Cancer, including Mutations and Treatments with Onco-Protein Inhibitors
Part III Basic Mechanisms of Tumor Progression
Some Results on the Population Behavior of Cancer Stem Cells
Glucose Metabolism in Multicellular Spheroids, ATP Production and Effects of Acidity
Cell-Cell Interactions in Solid Tumors - the Role of Cancer Stem Cells
Hybrid Cellular Potts Model for Solid Tumor Growth
Part IV Tumor-Immune System Interplay and Immunotherapy
Computational Models as Novel Tools for Cancer Vaccines
On the Dynamics of Tumor-Immune System Interactions and Combined Chemo- and Immunotherapy
Modeling the Kinetics of the Immune Response
Part V Computational Method for Improving Chemotherapy.- Optimizing Cancer Chemotherapy: from Mathematical Theories to Clinical Treatment
A Systems Biomedicine Approach for Chronotherapeutics Optimization: Focus on the Anticancer Drug Irinotecan
Modeling the Dynamics of HCV Infected Cells to Tailor Antiviral Therapy in Clinical Practice: Can This Approach Fit for Neoplastic Cells?
Introducing Drug Transport Early in the Design of Hypoxia Selective Anticancer Agents Using a Mathematical Modelling Approach
Top-Down Multiscale Simulation of Tumor Response to Treatment in the Context of In Silico Oncology. The Notion of Oncosimulator
Challenges in the Integration of Flow Cytometry and Time-Lapse Live Cell Imaging Data Using a Cell Proliferation Model

Part I Towards a Comprehensive Theory of Cancer Growth
Combining Game Theory and Graph Theory to Model Interactions between Cells in the Tumor Microenvironment
Growth as the Root of all Evil in Carcinomas: Synergy between pH Buffering and Anti-Angiogenesis prevents Emergence of Hallmarks of Cancer
Phase Transitions in Cancer
Part II Cancer Related Signalling Pathways
Spatio-Temporal Modelling of Intracellular Signalling Pathways: Transcription Factors, Negative Feedback Systems and Oscillations

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書誌ID:

IT00007145

ISBN:

9788847025714 [8847025710]      
9788847025707 [8847025702]